Glucose Transporter GLUT1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid(the oxidized form of vitamin C) into the brain1, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.

Description:
Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
DYT17 antibody, DYT18 antibody, erythrocyte/brain antibody, Erythrocyte/brain HepG2 glucose transporter antibody, Erythrocyte/hepatoma glucose transporter antibody, facilitated glucose transporter member 1 antibody, Glucose transporter 1 antibody, Glucose transporter type 1 antibody, Glucose transporter type 1 erythrocyte/brain antibody, Glucose transporter type 1, erythrocyte/brain antibody, GLUT antibody, GLUT-1 antibody, GLUT1 antibody, GLUT1DS antibody, GLUTB antibody, GT1 antibody, GTG1 antibody, Gtg3 antibody, GTR1_HUMAN antibody, HepG2 glucose transporter antibody, MGC141895 antibody, MGC141896 antibody, PED antibody, RATGTG1 antibody, SLC2A 1 antibody, SLC2A1 antibody, Solute carrier family 2(facilitated glucose transporter), member 1 antibody, Solute carrier family 2 antibody, Solute carrier family 2 facilitated glucose transporter member 1 antibody, Solute carrier family 2, facilitated glucose transporter member 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A1(477-492aa KTPEELFHPLGADSQV), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A1(477-492aa KTPEELFHPLGADSQV), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.