GLUD1 polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP11701b
Catalog Number: AC-AP11701b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20073
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20073
Applications: WB, IHC-P
Datasheet
Request Information
Background:
This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.
Other Names:
Glutamate dehydrogenase 1, mitochondrial, GDH 1, GLUD1, GLUD
Target/Specificity:
This GLUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the C-terminal region of human GLUD1.
Antigen Region:
438-465
Antigen Type: Synthetic Peptide
Gene Name: GLUD1
Gene ID: 2746
Primary Accession: P00367
NCBI Accession: NP_005262.1
Other Accession: P49448; P10860; P26443; P00368; P00366; NP_005262.1; Q6P3L9; P42174
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.
Other Names:
Glutamate dehydrogenase 1, mitochondrial, GDH 1, GLUD1, GLUD
Target/Specificity:
This GLUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the C-terminal region of human GLUD1.
Antigen Region:
438-465
Antigen Type: Synthetic Peptide
Gene Name: GLUD1
Gene ID: 2746
Primary Accession: P00367
NCBI Accession: NP_005262.1
Other Accession: P49448; P10860; P26443; P00368; P00366; NP_005262.1; Q6P3L9; P42174
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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