GLUL polyclonal, anti-human, mouse

Background:
This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate.

Alternative Name:
Glutamine synthetase, GS, Glutamate decarboxylase, Glutamate--ammonia ligase, GLNS, Gl Syn

Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200

Specificity: GLUL polyclonal antibody detects endogenous levels of GLUL protein.

Immunogen:
Recombinant full length Human GLUL.

MW: ~ 49 kDa

Swis Prot.: P15104

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.