GluR1 (clone ), anti-mouse, rat
€510.00
In stock
SKU
253162
Protein Family: Receptors and Channels
Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interaction
Description:
The glutamate receptor 1, a homo- or heterotetramer is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Phosphorylation of Ser831 has been linked to synaptic plasticity as well s learning and memory.
Alternate Names: Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1, Gria1, GluR1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P19490
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of rat GluR2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interaction
Description:
The glutamate receptor 1, a homo- or heterotetramer is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Phosphorylation of Ser831 has been linked to synaptic plasticity as well s learning and memory.
Alternate Names: Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1, Gria1, GluR1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P19490
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of rat GluR2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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