GluR1 (Ser831) polyclonal, anti-human, rat, dog, chicken
€536.00
In stock
SKU
252547
Protein Family: Receptors and Channels
Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interaction
Description:
The glutamate receptor 1, a homo- or heteroteramer, is an Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Phosphorylation of Ser831 has been linked to synaptic plasticity as well s learning and memory
Alternate Names: Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P19490
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser831 of rat GluR1-subunit.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interaction
Description:
The glutamate receptor 1, a homo- or heteroteramer, is an Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Phosphorylation of Ser831 has been linked to synaptic plasticity as well s learning and memory
Alternate Names: Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P19490
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser831 of rat GluR1-subunit.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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