GLUT-4 Polyclonal Antibody

Background:
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction, Stem Cells

Synonyms:
insulin-responsive, Glucose transporter GLUT 4, Glucose transporter type 4, Glucose transporter type 4 insulin responsive, GLUT 4, GLUT-4, GLUT4, GTR4, Insulin responsive glucose transporter type 4, kug, SLC 2A4, SLC2A4, solute carrier family 2 (facilitated glucose transporter) member 4, Solute carrier family 2 member 4, Solute carrier family 2, facilitated glucose transporter member 4

Immunogen: Synthesized peptide derived from the N-terminal region of human Glut4.

Swissprot: P14672

Calculated MW: 55 kDa
Observed MW: 56 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.

Concentration: 1 mg/mL
Dilution: WB 1:500-2000, IHC 1:50-300, ELISA 1:10000-20000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/32455814/