GLUT4 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
GLUT4, also known as SLC2A4 or solute carrier family 2 (facilitated glucose transporter) member 4, is a protein that in humans is encoded by the GLUT4 gene. It is mapped to 17p13.1. This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

Description:
Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
insulin-responsive antibody, Glucose transporter GLUT 4 antibody, Glucose transporter type 4 antibody, Glucose transporter type 4 insulin responsive antibody, GLUT 4 antibody, GLUT-4 antibody, GLUT4 antibody, GTR4_HUMAN antibody, kug antibody, SLC 2A4 antibody, SLC2A4 antibody, solute carrier family 2 (facilitated glucose transporter) member 4 antibody, Solute carrier family 2, facilitated glucose transporter member 4 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human GLUT4 recombinant protein (Position: N333-D509). Human GLUT4 shares 97% amino acid (aa) sequence identity with mouse GLUT4.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.