STAT3 monoclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP52814
Catalog Number: AC-AP55157
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
Datasheet
Request Information
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
Datasheet
Request Information
Background:
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Other Names:
1110034C02Rik;Acute Phase Response Factor;Acute-phase response factor;APRF;AW109958;DNA binding protein APRF;FLJ20882;HIES;MGC128731; MGC16063;MGC93551;Signal transducer and activator of transcription 3 (acute-phase response factor);Signal transducer and activator of transcription 3;STAT 3;Stat3;STAT3_HUMAN;Transcription factor.
Antigen Type: Recombinant Protein
Antigen Type: STAT3 {ECO:0000303|PubMed:9630560, ECO:0000312|HGNC:HGNC:11364}
Gene ID: 6774
Primary Accession: P40763
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Other Names:
1110034C02Rik;Acute Phase Response Factor;Acute-phase response factor;APRF;AW109958;DNA binding protein APRF;FLJ20882;HIES;MGC128731; MGC16063;MGC93551;Signal transducer and activator of transcription 3 (acute-phase response factor);Signal transducer and activator of transcription 3;STAT 3;Stat3;STAT3_HUMAN;Transcription factor.
Antigen Type: Recombinant Protein
Antigen Type: STAT3 {ECO:0000303|PubMed:9630560, ECO:0000312|HGNC:HGNC:11364}
Gene ID: 6774
Primary Accession: P40763
| Is Featured? | No |
|---|
Write Your Own Review