Glutaminase GLS monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO14085
Catalog Number: AC-ABO14085
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC
Datasheet
Request Information
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC
Datasheet
Request Information
Description: Anti-Glutaminase GLS Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
Other Names: Glutaminase kidney isoform, mitochondrial, GLS, 3.5.1.2, K-glutaminase, L-glutamine amidohydrolase, Glutaminase kidney isoform, mitochondrial 68 kDa chain, GLS, GLS1, KIAA0838
Clone Name(s):
Clone: FIA-7
Subcellular Localization: Isoform 1: Cytoplasm, cytosol.
Tissue Specificity: Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle..
Gene ID: 2744
Immunogen: A synthesized peptide derived from human Glutaminase
Calculated MW: 73461
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
Other Names: Glutaminase kidney isoform, mitochondrial, GLS, 3.5.1.2, K-glutaminase, L-glutamine amidohydrolase, Glutaminase kidney isoform, mitochondrial 68 kDa chain, GLS, GLS1, KIAA0838
Clone Name(s):
Clone: FIA-7
Subcellular Localization: Isoform 1: Cytoplasm, cytosol.
Tissue Specificity: Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle..
Gene ID: 2744
Immunogen: A synthesized peptide derived from human Glutaminase
Calculated MW: 73461
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
| Is Featured? | No |
|---|
Write Your Own Review