Glutaredoxin 1 (clone 28C3), anti-human antibody
€355.00
In stock
SKU
AC-ABV11173-100
Catalog Number: AC-ABV11173-100
Size: 100 µl
Host: Mouse IgG
Applications: E, IP
Datasheet
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Size: 100 µl
Host: Mouse IgG
Applications: E, IP
Datasheet
Request Information
Background:
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress. Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Other Names:
Thioltransferase-1, GLRX, GRX
Primary Accession: P35754
Gene Name: GLRX
Gene ID: 2745
Concentration (mg/ml): 1 mg/ml
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress. Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Other Names:
Thioltransferase-1, GLRX, GRX
Primary Accession: P35754
Gene Name: GLRX
Gene ID: 2745
Concentration (mg/ml): 1 mg/ml
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