Glutathione Reductase (clone 2B3), anti-human antibody
€355.00
In stock
SKU
AC-ABV11174-100
Catalog Number: AC-ABV11174-100
Size: 100 µl
Host: Mouse IgG
Applications: E, IP
Datasheet
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Size: 100 µl
Host: Mouse IgG
Applications: E, IP
Datasheet
Request Information
Background:
Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG). In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.
Other Names:
GSR, GLUR, GRD1
Primary Accession: P00390
Gene Name: GSR
Gene ID: 2936
Concentration (mg/ml): 1 mg/ml
Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG). In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.
Other Names:
GSR, GLUR, GRD1
Primary Accession: P00390
Gene Name: GSR
Gene ID: 2936
Concentration (mg/ml): 1 mg/ml
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