Glutathione S Transferase theta 1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
GSTT1(glutathione S-transferase theta 1), also known as GST class-theta-1, Glutathione transferase T1-1, is an enzyme that in humans is encoded by the GSTT1 gene. It is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human theta-class GST, termed GSTT1 has 239-amino acid GSTT1 protein shares 80% sequence identity with the rat homolog. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

Description:
Rabbit IgG polyclonal antibody for Glutathione S-transferase theta-1 (GSTT1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
EC 2.5.1.18 antibody, Glutathione S transferase 5 antibody, Glutathione S transferase theta 1 antibody, Glutathione S-transferase theta-1 antibody, Glutathione transferase T1 1 antibody, Glutathione transferase T1-1 antibody, GST 5 5 antibody, GST CL1 antibody, GST class theta 1 antibody, GST class-theta-1 antibody, GSTT1 antibody, GSTT1_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Glutathione S Transferase theta 1(96-112aa DEYLAWQHTTLRRSCLR), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.