Glycerate Kinase rabbit polyclonal, anti-human, mouse, rat

Backgroud: This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],catalytic activity:ATP + (R)-glycerate = ADP + 3-phospho-(R)-glycerate.,disease:Defects in GLYCTK are the cause of D-glyceric acidemia [MIM:220120]. It is characterized by nonketotic hyperglycinemia with the excretion of D-glyceric acid in the urine and the presence of this substance in the serum.,similarity:Belongs to the glycerate kinase type-2 family.,tissue specificity:Widely expressed.,

Synonyms: GLYCTK, HBEBP4, LP5910, Glycerate kinase, HBeAg-binding protein 4

Gene Name: GLYCTK

Gene ID: 132158

SwissProt ID: Q8IVS8

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.