Glypican-3 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES3936
Catalog Number: ELK-ES3936
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
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Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
glypican 3(GPC3) Homo sapiens Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],
Alternative Names:
GPC3, OCI5, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GPC3. AA range:461-510
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 70
GeneID: GPC3
Storage: -20°C/1 year
NOTE: For Research Use Only
glypican 3(GPC3) Homo sapiens Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],
Alternative Names:
GPC3, OCI5, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GPC3. AA range:461-510
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 70
GeneID: GPC3
Storage: -20°C/1 year
NOTE: For Research Use Only
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