GlyRβ Polyclonal Antibody

Background:
glycine receptor beta(GLRB) Homo sapiens This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Alternative Names:
GLRB, Glycine receptor subunit beta, Glycine receptor 58 kDa subunit

Immunogen: The antiserum was produced against synthesized peptide derived from human GLRB. AA range:211-260

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 56

GeneID: GLRB

Storage: -20°C/1 year

NOTE: For Research Use Only