GM2A Polyclonal Antibody

Background:
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
GM2A, GM2-AP, SAP-3

Immunogen: Recombinant fusion protein of human GM2A (NP_000396.2).

Swissprot: P17900
Gene ID: 2760

Calculated MW: 20 kDa
Observed MW: 26 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.