Caspase-9 monoclonal, anti-human

Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP).

Other Names:
APAF 3;APAF-3;APAF3;Apoptosis related cysteine peptidase;Apoptotic protease activating factor 3;Apoptotic protease Mch 6;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;CASP 9;CASP-9;CASP9;CASP9_HUMAN;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9;Caspase-9 subunit p10;Caspase9;ICE LAP6;ICE like apoptotic protease 6;ICE-LAP6;ICE-like apoptotic protease 6;MCH6;PPP1R56;protein phosphatase 1, regulatory subunit 56;RNCASP9

Antigen Type: Recombinant Protein

Antigen Type: CASP9
Gene ID: 842
Primary Accession: P55211