GMDS Polyclonal Antibody

Background:
GDP-mannose 4, 6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3, 5-epimerase, 4-reductase, designated FX in humans (MIM 137020).

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
GDP D mannose dehydratase, GDP mannose 4 6 dehydratase, GDP-D-mannose dehydratase, GDP-mannose 4, 6 dehydratase, GMD, Gmds, GMDS, OTTHUMP00000017756, OTTHUMP00000232770, SDR3E1, Short chain dehydrogenase/reductase family 3E member 1

Immunogen: Fusion protein of human GMDS

Swissprot: O60547
Gene Accession: BC000117

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.26 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.