GNA11 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

Synonyms: FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2

Cellular Location: Cell membrane Cytoplasm Lipid-anchor

Immunogen:
Recombinant protein of human GNA11

Gene Symbol: GNA11

Gene ID: 2767

Swiss prot: P29992

Calculated MW: 42kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.