GNAI3 Polyclonal Antibody

Background:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.

Research Area: Cancer, Signal Transduction

Synonyms:
GNAI3, 87U6, ARCND1

Immunogen: A synthetic peptide of human GNAI3 (NP_006487.1).

Swissprot: P08754
Gene ID: 2773

Calculated MW: 40 kDa
Observed MW: 41-45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.