GNAO1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7367
Background:
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.
Alternative Name:
DKFZp686O0962, G alpha o, G protein alpha 0, Galphao, GNAO 1, GNAO, GNAO_HUMAN, GNAO1, Go alpha, Guanine nucleotide binding protein (G protein) alpha activating activity polypeptide O, Guanine nucleotide binding protein alpha activating polypeptide, Guanine nucleotide binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(o) subunit alpha,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: GNAO1 polyclonal antibody detects endogenous levels of GNAO1 protein.
Immunogen:
Recombinant full length Human GNAO1.
MW: ~40 kDa
Swis Prot.: P09471
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.
Alternative Name:
DKFZp686O0962, G alpha o, G protein alpha 0, Galphao, GNAO 1, GNAO, GNAO_HUMAN, GNAO1, Go alpha, Guanine nucleotide binding protein (G protein) alpha activating activity polypeptide O, Guanine nucleotide binding protein alpha activating polypeptide, Guanine nucleotide binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(o) subunit alpha,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: GNAO1 polyclonal antibody detects endogenous levels of GNAO1 protein.
Immunogen:
Recombinant full length Human GNAO1.
MW: ~40 kDa
Swis Prot.: P09471
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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