GNB1L Polyclonal Antibody

Background:
This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene.

Research Area: Signal transduction

Synonyms:
DGCRK3, ESTM55 , fb98e06, fj09d12, FKSG1, G protein subunit beta-like protein 1, G-protein beta subunit-like protein, GNB1L, GNB1L, guanine nucleotide binding protein (G protein), beta polypeptide 1-like, guanine nucleotide binding protein beta-subunit-like polypeptide, Guanine nucleotide-binding protein subunit beta-like protein 1, GY2, KIAA1645, WD repeat-containing protein 14, WD40 repeat-containing protein deleted in VCFS, WDR14, WDVCF, wu:fb98e06, wu:fj09d12 , zgc:55774

Immunogen: Synthetic peptide of human GNB1L

Swissprot: Q9BYB4
Gene Accession: NP443730

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.