GNE polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP5318B
Catalog Number: AC-AP5318B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26213
Applications: FC, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26213
Applications: FC, WB
Datasheet
Request Information
Background:
GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells.
Other Names:
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UDP-GlcNAc-2-epimerase/ManAc kinase, UDP-N-acetylglucosamine 2-epimerase (hydrolyzing), UDP-GlcNAc-2-epimerase, Uridine diphosphate-N-acetylglucosamine-2-epimerase, N-acetylmannosamine kinase, ManAc kinase, GNE, GLCNE
Target/Specificity:
This GNE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 580-607 amino acids from the C-terminal region of human GNE.
Antigen Region:
580-607
Antigen Type: Synthetic Peptide
Gene Name: GNE (HGNC:23657)
Gene ID: 10020
Primary Accession: Q9Y223
NCBI Accession: NP_001121699.1;NP_001177312.1;NP_001177313.1;NP_001177317.1;NP_005467.1
Other Accession: O35826; Q91WG8; Q7TQ49; NP_005467.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells.
Other Names:
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UDP-GlcNAc-2-epimerase/ManAc kinase, UDP-N-acetylglucosamine 2-epimerase (hydrolyzing), UDP-GlcNAc-2-epimerase, Uridine diphosphate-N-acetylglucosamine-2-epimerase, N-acetylmannosamine kinase, ManAc kinase, GNE, GLCNE
Target/Specificity:
This GNE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 580-607 amino acids from the C-terminal region of human GNE.
Antigen Region:
580-607
Antigen Type: Synthetic Peptide
Gene Name: GNE (HGNC:23657)
Gene ID: 10020
Primary Accession: Q9Y223
NCBI Accession: NP_001121699.1;NP_001177312.1;NP_001177313.1;NP_001177317.1;NP_005467.1
Other Accession: O35826; Q91WG8; Q7TQ49; NP_005467.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review