GNPDA1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1461a
Background:
Glucosamine-6-phosphate deaminase (GNPDA) catalyzes the conversion of glucosamine-6-phosphate to fructose-6-phosphate, a reaction that under physiological conditions proceeds to the formation of fructose-6-phosphate. GNPDA is the sole enzyme linking hexosamine systems with glycolytic pathways, and has been proposed to provide a source of energy in the form of phosphosugar derived from the catabolism of hexosamines found in glycoproteins, glycolipids, and sialic acid-containing macromolecules. GNPDA localizes close to the developing acrosome vesicle and in spermatozoa close to the acrosomal region, and may play a role in the acrosome reaction.
Other Names:
Glucosamine-6-phosphate isomerase 1, Glucosamine-6-phosphate deaminase 1, GNPDA 1, GlcN6P deaminase 1, Oscillin, GNPDA1, GNPI, HLN, KIAA0060
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1461a was selected from the N-term region of human GNPDA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GNPDA1 {ECO:0000303|PubMed:26887390, ECO:0000312|HGNC:HGNC:4417}
Gene ID: 10007
Primary Accession: P46926
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Glucosamine-6-phosphate deaminase (GNPDA) catalyzes the conversion of glucosamine-6-phosphate to fructose-6-phosphate, a reaction that under physiological conditions proceeds to the formation of fructose-6-phosphate. GNPDA is the sole enzyme linking hexosamine systems with glycolytic pathways, and has been proposed to provide a source of energy in the form of phosphosugar derived from the catabolism of hexosamines found in glycoproteins, glycolipids, and sialic acid-containing macromolecules. GNPDA localizes close to the developing acrosome vesicle and in spermatozoa close to the acrosomal region, and may play a role in the acrosome reaction.
Other Names:
Glucosamine-6-phosphate isomerase 1, Glucosamine-6-phosphate deaminase 1, GNPDA 1, GlcN6P deaminase 1, Oscillin, GNPDA1, GNPI, HLN, KIAA0060
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1461a was selected from the N-term region of human GNPDA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GNPDA1 {ECO:0000303|PubMed:26887390, ECO:0000312|HGNC:HGNC:4417}
Gene ID: 10007
Primary Accession: P46926
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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