GNRHR polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP18314a
Catalog Number: AC-AP18314a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20076
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20076
Applications: WB
Datasheet
Request Information
Background:
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.
Other Names:
Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R, GNRHR, GRHR
Target/Specificity:
This GNRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GNRHR.
Antigen Region:
49-77
Antigen Type: Synthetic Peptide
Gene Name: GNRHR
Gene ID: 2798
Primary Accession: P30968
NCBI Accession: NP_000397.1;NP_001012781.1
Other Accession: NP_000397
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.
Other Names:
Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R, GNRHR, GRHR
Target/Specificity:
This GNRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GNRHR.
Antigen Region:
49-77
Antigen Type: Synthetic Peptide
Gene Name: GNRHR
Gene ID: 2798
Primary Accession: P30968
NCBI Accession: NP_000397.1;NP_001012781.1
Other Accession: NP_000397
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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