GNS polyclonal, anti-human, mouse, rat

Background:
The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

Alternative Name:
N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS

Application Dilution: WB: 1:500 - 1:2000

Specificity: GNS polyclonal antibody detects endogenous levels of GNS protein.

Immunogen:
Recombinant full length Human GNS.

MW: ~ 62kDa

Swis Prot.: P15586

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.