GOLPH3 polyclonal, anti-human, mouse, rat

Background:
GOLPH3 (golgi phosphoprotein 3), also known as GOPP1, GPP34 or MIDAS, is a 298 amino acid protein that localizes to both the cytoplasm and the Golgi stack membrane where it is thought to play a regulatory role in protein trafficking within the Golgi. GOLPH3 is subject to post-translational phosphorylation and is encoded by a gene which maps to human chromosome 5. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Alternative Name:
MIDAS, GOLPH3, GPP34, Coat protein, Coat protein GPP34, FLJ90675, Golgi associated protein, Golgi peripheral membrane protein 1, 34 kDa, Golgi phosphoprotein 3 (coat protein), Golgi phosphoprotein 3, Golgi protein, GOLP3, Golph3, GOPP1, GPP34, MIDAS, Mitochondrial DNA absence factor,

Application Dilution:
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: GOLPH3 polyclonal antibody detects endogenous levels of GOLPH3 protein.

Immunogen:
Recombinant protein

MW: 34 kDa

Swiss-Prot: Q9H4A6(Human) Q9CRA5(Mouse) Q9ERE4(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.