gp100/SILV [clone PMEL/783], anti-human

Description: Cytotoxic T-lymphocytes (CTL’s) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens, and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.Localization: cytoplasmDilution: 50-200Positive Control: melanomaHIER: citrate pH6.0 or EDTA pH8.0Status: RUO