gp120 polyclonal, anti-virus
€484.00
In stock
SKU
253891
Protein Family: Cellular Antigens
Pathway and Disease: Immune System, Infectious Diseases, Signaling Molecules and Interaction
Description:
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Alternate Names: gp120 , HIV-1 glycoprotein 120
Application Notes: E: 1:5000-1:10,000; WB: 1:1000-1:2000
Accession No.: AAT67551
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region (V1/V2 loop) of HIV-1 gp120.
Format: Each vial contains 0.1 mg (1 mg/ml) IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Immune System, Infectious Diseases, Signaling Molecules and Interaction
Description:
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Alternate Names: gp120 , HIV-1 glycoprotein 120
Application Notes: E: 1:5000-1:10,000; WB: 1:1000-1:2000
Accession No.: AAT67551
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region (V1/V2 loop) of HIV-1 gp120.
Format: Each vial contains 0.1 mg (1 mg/ml) IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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