GP6 Polyclonal Antibody

Background:
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cardiovascular

Synonyms:
Glycoprotein 6, Glycoprotein VI, GP6, GPIV, GPVI, GPVI, MGC138168, Platelet collagen receptor, Platelet glycoprotein VI, Platelet glycoprotein VI precursor

Immunogen: Synthetic peptide of human GP6

Swissprot: Q9HCN6
Gene Accession: NP057447

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.