GPA33 Polyclonal Antibody

Background:
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.

Research Area: Cancer, Immunology

Synonyms:
A33, Cell surface A33 antigen, Cell surface A33 antigen precursor, Glycoprotein A33 (transmembrane), Glycoprotein A33, Gpa33, GPA33, MGC129986, MGC129987, OTTHUMP00000032346, Transmembrane glycoprotein A33

Immunogen: Fusion protein of human GPA33

Swissprot: Q99795
Gene Accession: BC069723

Calculated MW: 36 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.