GPCR RDC1 polyclonal, anti-human, mouse, rat

Background:
Members of the C-X-C or α chemokine family are characterized by a pair of cysteine residues separated by a single amino acid and primarily function as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins and include proteins such as IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). C-X-C chemokine receptor type 7 (CXCR-7), also known as RDC-1, is a 362 amino acid receptor for SDF-1. Initially identified as a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor. CXCR-7, with CSCR-4, also acts as a coreceptor for human immunodeficiency viruses (HIV). Highly expressed in monocytes, B-cells and basophils, and highly active in various biological processes, including cell growth, cell adhesion and tumor growth, CXCR-7 may play a role in tumorigenesis.

Alternative Name:
CXC-R7, CXCR-7, RDC-1, ACKR3, ACKR3, atypical chemokine receptor 3, C X C chemokine receptor type 7, C-X-C chemokine receptor type 7, Chemokine (C-X-C motif) receptor 7, Chemokine C X C motif receptor 7, Chemokine orphan receptor 1, CMKOR1, CXC R7, CXC-R7, CXCR 7, CXCR-7, CXCR7, CXCR7, G protein coupled receptor 159, G protein coupled receptor, G protein coupled receptor RDC1 homolog, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, GPR159, GPRN1, RDC 1, RDC-1, RDC1,

Application Dilution:
WB:1:1,000-1:5,000
FC:1:10-1:100

Specificity: GPCR RDC1 polyclonal antibody detects endogenous levels of GPCR RDC1 protein.

Immunogen:
recombinant protein

MW: 41 kDa

Swiss-Prot: P25106(Human) P56485(Mouse) O89039(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.