GPD1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7810
Background:
Voltage-gated sodium channels drive the initial depolarization phase of the cardiac action potential, therefore, critically determine conduction of excitation through the heart. As a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family, glycerol-3-phosphate dehydrogenase 1 (GPD1) is a 349 amino acid cytoplasmic protein that catalyzes the formation of glycerone phosphate and NADH from sn-glycerol 3-phosphate and NAD+. Inhibited by zinc ions and sulfate, GPD1 exists as a homodimer and may have similar functions as GPD1L (glycerol-3 phosphate dehydrogenase like). GPD1L is thought to affect trafficking of the cardiac sodium current to the cell surface and mutations in the gene encoding GPD1L are thought to be involved in sudden infant death syndrome (SIDS).
Alternative Name:
cytoplasmic, FLJ26652, G3PD, Gdc-1, Gdc1, Gdp1, Glycerol 3 phosphate dehydrogenase 1, Glycerol 3 phosphate dehydrogenase cytosolic, Glycerol 3 phosphate dehydrogenase soluble, Glycerol-3-phosphate dehydrogenase [NAD+], Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, Glycerol-3-phosphate dehydrogenase 1 (soluble), Glycerol-3-phosphate dehydrogenase, Glycerol-3-phosphate dehydrogenase, soluble, Glycerphosphate dehydrogenase, GPD-C, gpd1, Gpd1 protein, Gpd3, GPDA_HUMAN, Gpdc, GPDH, GPDH-C, Gpdhc, HTGTI, KIAA4010, MGPD, mKIAA4010,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: GPD1 polyclonal antibody detects endogenous levels of GPD1 protein.
Immunogen:
Recombinant full length Human GPD1.
MW: ~ 38 kDa
Swis Prot.: P21695
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Voltage-gated sodium channels drive the initial depolarization phase of the cardiac action potential, therefore, critically determine conduction of excitation through the heart. As a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family, glycerol-3-phosphate dehydrogenase 1 (GPD1) is a 349 amino acid cytoplasmic protein that catalyzes the formation of glycerone phosphate and NADH from sn-glycerol 3-phosphate and NAD+. Inhibited by zinc ions and sulfate, GPD1 exists as a homodimer and may have similar functions as GPD1L (glycerol-3 phosphate dehydrogenase like). GPD1L is thought to affect trafficking of the cardiac sodium current to the cell surface and mutations in the gene encoding GPD1L are thought to be involved in sudden infant death syndrome (SIDS).
Alternative Name:
cytoplasmic, FLJ26652, G3PD, Gdc-1, Gdc1, Gdp1, Glycerol 3 phosphate dehydrogenase 1, Glycerol 3 phosphate dehydrogenase cytosolic, Glycerol 3 phosphate dehydrogenase soluble, Glycerol-3-phosphate dehydrogenase [NAD+], Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, Glycerol-3-phosphate dehydrogenase 1 (soluble), Glycerol-3-phosphate dehydrogenase, Glycerol-3-phosphate dehydrogenase, soluble, Glycerphosphate dehydrogenase, GPD-C, gpd1, Gpd1 protein, Gpd3, GPDA_HUMAN, Gpdc, GPDH, GPDH-C, Gpdhc, HTGTI, KIAA4010, MGPD, mKIAA4010,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: GPD1 polyclonal antibody detects endogenous levels of GPD1 protein.
Immunogen:
Recombinant full length Human GPD1.
MW: ~ 38 kDa
Swis Prot.: P21695
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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