GPHN Polyclonal Antibody

Background:
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.

Synonyms:
GPHN, GEPH, GPH, GPHRYN, HKPX1, MOCODC, gephyrin

Immunogen: Recombinant fusion protein of human GPHN (NP_065857.1).

Swissprot: Q9NQX3
Gene ID: 10243

Calculated MW: 79 kDa/83 kDa
Observed MW: 103 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.