GPI (clone 1B7D7), anti-human
€539.00
In stock
SKU
252765
Protein Family: Enzymes
Pathway and Disease: Carbohydrate Metabolism
Description:
GPI (Glucose-6-phosphate isomerase) belongs to the GPI family whose members are multifunctional phosphoglucose isomerase proteins. GPI is involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein has different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Alternate Names: Glucose-6-phosphate isomerase, Autocrine motility factor, AMF, Neuroleukin, NLK, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Sperm antigen 36, SA-36, GNPI, GPI
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000
Accession No.: P06744
Antigen: Purified recombinant fragment of human GPI expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Carbohydrate Metabolism
Description:
GPI (Glucose-6-phosphate isomerase) belongs to the GPI family whose members are multifunctional phosphoglucose isomerase proteins. GPI is involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein has different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Alternate Names: Glucose-6-phosphate isomerase, Autocrine motility factor, AMF, Neuroleukin, NLK, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Sperm antigen 36, SA-36, GNPI, GPI
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000
Accession No.: P06744
Antigen: Purified recombinant fragment of human GPI expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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