GPI polyclonal (C-term), anti-human, mouse

GPI polyclonal (C-term), anti-human, mouse

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In stock
SKU
AC-AP9786b
Catalog Number: AC-AP9786b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24626
Applications: WB, FC
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Background:
GPI belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Other Names:
Glucose-6-phosphate isomerase, GPI, Autocrine motility factor, AMF, Neuroleukin, NLK, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Sperm antigen 36, SA-36, GPI

Target/Specificity:
This GPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-473 amino acids from the C-terminal region of human GPI.

Antigen Region:
445-473

Antigen Type: Synthetic Peptide

Gene Name: GPI {ECO:0000303|PubMed:2387591, ECO:0000312|HGNC:HGNC:4458}
Gene ID: 2821
Primary Accession: P06744
NCBI Accession: NP_000166.2;NP_001171651.1
Other Accession: Q4R591
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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