GPNMB antibody (clone 1A8), anti-human
€435.00
In stock
SKU
AC-AT2244a
Catalog Number: AC-AT2244a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT2244a">Request Information
Background:
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Transmembrane glycoprotein NMB, Transmembrane glycoprotein HGFIN, GPNMB, HGFIN, NMB
Antigen Type:
Recombinant Protein
Gene Name: GPNMB
Gene ID: 10457
NCBI Accession: NP_001005340.1;NP_002501.1
Primary Accession: Q14956
Other Accession: NM_001005340
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Transmembrane glycoprotein NMB, Transmembrane glycoprotein HGFIN, GPNMB, HGFIN, NMB
Antigen Type:
Recombinant Protein
Gene Name: GPNMB
Gene ID: 10457
NCBI Accession: NP_001005340.1;NP_002501.1
Primary Accession: Q14956
Other Accession: NM_001005340
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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