GPNMB Polyclonal Antibody

Background:
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Immunology, Cancer

Synonyms:
Glycoprotein nmb, Glycoprotein nmb like protein, Gpnmb, HGFIN, NMB, Osteoactivin, Transmembrane glycoprotein, Transmembrane glycoprotein HGFIN, Transmembrane glycoprotein NMB,

Immunogen: Recombinant Human Transmembrane glycoprotein NMB protein

Swissprot: Q14956
Gene ID: 10457

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Concentration: 1mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20℃. Avoid freeze / thaw cycles.