GPNMB polyclonal (C-term), anti-human
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In stock
SKU
AC-AP17232b
Catalog Number: AC-AP17232b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36977
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36977
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Transmembrane glycoprotein NMB, Transmembrane glycoprotein HGFIN, GPNMB, HGFIN, NMB
Target/Specificity:
This GPNMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human GPNMB.
Antigen Region:
541-569
Antigen Type: Synthetic Peptide
Gene Name: GPNMB
Gene ID: 10457
Primary Accession: Q14956
NCBI Accession: NP_001005340.1;NP_002501.1
Other Accession: NP_002501.1;NP_001005340.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
Transmembrane glycoprotein NMB, Transmembrane glycoprotein HGFIN, GPNMB, HGFIN, NMB
Target/Specificity:
This GPNMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human GPNMB.
Antigen Region:
541-569
Antigen Type: Synthetic Peptide
Gene Name: GPNMB
Gene ID: 10457
Primary Accession: Q14956
NCBI Accession: NP_001005340.1;NP_002501.1
Other Accession: NP_002501.1;NP_001005340.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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