GPR124 polyclonal, anti-human, mouse

Background:
TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Synonyms: TEM5

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human GPR124

Gene Symbol: GPR124

Gene ID: 25960

Swiss prot: Q96PE1

Calculated MW: 143 kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-300,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.