GRIN1 polyclonal, anti-human, mouse, rat

GRIN1 polyclonal, anti-human, mouse, rat

€470.00
In stock
SKU
AC-AP74253
Catalog Number: AC-AP61531
Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC, IHC
Datasheet
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Background:
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761).

Other Names:
Glutamate [NMDA] receptor subunit zeta-1 (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)

Antigen Type: synthetic peptide

Antigen Type: GRIN1
Gene ID: 2902
Primary Accession: Q05586
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