GPR153 Polyclonal Antibody

Background:
This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells.

Synonyms:
DKFZp762B2210, G Protein Coupled Receptor 153, G Protein Coupled Receptor LS19072, G protein coupled receptor PGR1, G-protein coupled receptor PGR1, GP153, Gpr153, PGR1, Probable G-protein coupled receptor 153

Immunogen: Synthetic peptide of human GPR153

Swissprot: Q6NV75
Gene Accession: NP997253

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.