GPR18 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5744
Background:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR18 (G protein-coupled receptor 18), also known as GPCRW, is a 331 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor family. Expressed abundantly in spleen and testis, GPR18 functions as a receptor for N-arachidonyl glycine and is thought to contribute to the regulation of the immune system. GPR18 activity is mediated by G proteins that specifically inhibit adenylyl cyclase.
Alternative Name:
N-arachidonyl glycine receptor, NAGly receptor, G-protein coupled receptor 18, GPR18, GPCRW
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: GPR18 polyclonal antibody detects endogenous levels of GPR18 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 239-284 of Human GPR18.
MW: ~ 35 kDa
Swis Prot.: Q14330
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR18 (G protein-coupled receptor 18), also known as GPCRW, is a 331 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor family. Expressed abundantly in spleen and testis, GPR18 functions as a receptor for N-arachidonyl glycine and is thought to contribute to the regulation of the immune system. GPR18 activity is mediated by G proteins that specifically inhibit adenylyl cyclase.
Alternative Name:
N-arachidonyl glycine receptor, NAGly receptor, G-protein coupled receptor 18, GPR18, GPCRW
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: GPR18 polyclonal antibody detects endogenous levels of GPR18 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 239-284 of Human GPR18.
MW: ~ 35 kDa
Swis Prot.: Q14330
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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