GPR43 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009],function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen.,

Synonyms: FFAR2, GPR43, Free fatty acid receptor 2, G-protein coupled receptor 43

Gene Name: FFAR2

Gene ID: 2867

SwissProt ID: O15552

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.