GPR77 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP20046b
Background:
The anaphylatoxins C3a (see MIM 120700), C4a (see MIM120810), and C5a are cationic fragments generated during thecomplement cascade that participate in host defense. In the case ofinappropriate complement activation, anaphylatoxins may be involvedin autoimmunity and sepsis. C5L2 is coexpressed with the C5areceptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophilsand may modulate C5AR activity (Gerard et al., 2005 [PubMed16204243]).
Other Names:
C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
Target/Specificity:
The synthetic peptide sequence is selected from aa 312-325 of HUMAN C5AR2
Gene Name: C5AR2
Gene ID: 27202
Primary Accession: Q9P296
Other Accession: NP_060955.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The anaphylatoxins C3a (see MIM 120700), C4a (see MIM120810), and C5a are cationic fragments generated during thecomplement cascade that participate in host defense. In the case ofinappropriate complement activation, anaphylatoxins may be involvedin autoimmunity and sepsis. C5L2 is coexpressed with the C5areceptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophilsand may modulate C5AR activity (Gerard et al., 2005 [PubMed16204243]).
Other Names:
C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
Target/Specificity:
The synthetic peptide sequence is selected from aa 312-325 of HUMAN C5AR2
Gene Name: C5AR2
Gene ID: 27202
Primary Accession: Q9P296
Other Accession: NP_060955.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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