GPR77 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP20046b
Catalog Number: AC-AP20046b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42221
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42221
Applications: WB
Datasheet
Request Information
Background:
The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).
Other Names:
C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
Target/Specificity:
This GPR77 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77.
Antigen Region:
297-325
Antigen Type: Synthetic Peptide
Gene Name: C5AR2
Gene ID: 27202
Primary Accession: Q9P296
NCBI Accession: NP_001258678.1;NP_001258679.1;NP_060955.1
Other Accession: NP_060955.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).
Other Names:
C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
Target/Specificity:
This GPR77 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77.
Antigen Region:
297-325
Antigen Type: Synthetic Peptide
Gene Name: C5AR2
Gene ID: 27202
Primary Accession: Q9P296
NCBI Accession: NP_001258678.1;NP_001258679.1;NP_060955.1
Other Accession: NP_060955.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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