GPS2 antibody (clone 3C4), anti-human
€435.00
In stock
SKU
AC-AT2253a
Catalog Number: AC-AT2253a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT2253a">Request Information
Background:
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Other Names:
G protein pathway suppressor 2, GPS-2, GPS2
Antigen Type:
Recombinant Protein
Gene Name: GPS2 (HGNC:4550)
Gene ID: 2874
NCBI Accession: NP_004480.1
Primary Accession: Q13227
Other Accession: BC013652
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Other Names:
G protein pathway suppressor 2, GPS-2, GPS2
Antigen Type:
Recombinant Protein
Gene Name: GPS2 (HGNC:4550)
Gene ID: 2874
NCBI Accession: NP_004480.1
Primary Accession: Q13227
Other Accession: BC013652
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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