GPS2 Polyclonal Antibody

Background:
G protein pathway suppressor 2(GPS2) Homo sapiens This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008],

Alternative Names:
GPS2, G protein pathway suppressor 2, GPS-2

Immunogen: The antiserum was produced against synthesized peptide derived from human GPS2. AA range:11-60

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 40

GeneID: GPS2

Storage: -20°C/1 year

NOTE: For Research Use Only