GPSM2 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cell Biology, Signal transduction

Synonyms:
GPSM2, CMCS, DFNB82, LGN, PINS

Immunogen: Recombinant fusion protein of human GPSM2 (NP_037428.3).

Swissprot: P81274
Gene ID: 29899

Calculated MW: 76 kDa
Observed MW: 76 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.