GPX4 Antibody (Center) Blocking peptide

Background:
Glutathione peroxidase catalyzes the reduction of hydrogenperoxide, organic hydroperoxide, and lipid peroxides by reducedglutathione and functions in the protection of cells againstoxidative damage. Human plasma glutathione peroxidase has beenshown to be a selenium-containing enzyme and the UGA codon istranslated into a selenocysteine. Through alternative splicing andtranscription initiation, rat produces proteins that localize tothe nucleus, mitochondrion, and cytoplasm. In humans, experimentalevidence for alternative splicing exists; alternative transcriptioninitiation and the cleavage sites of the mitochondrial and nucleartransit peptides need to be experimentally verified. [provided byRefSeq].

Other Names:
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial, PHGPx, Glutathione peroxidase 4, GPx-4, GSHPx-4, GPX4

Gene Name: GPX4 {ECO:0000303|PubMed:9705830, ECO:0000312|HGNC:HGNC:4556}

Gene ID: 2879
Primary Accession: P36969
Other Accession: NP_001034937.1;NP_001034936.1;NP_002076.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.